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Home - Products - Microbiology/Virology - HSV - Ardisiacrispin A

Ardisiacrispin A

CAS No. 23643-61-0

Ardisiacrispin A( Deglucocyclamin | LTS-4 | Saxifragifolin B )

Catalog No. M24075 CAS No. 23643-61-0

Ardisiacrispin A has cytotoxic activity toward HepG2 cancer cell with the GI(50) value of 1.56μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Ardisiacrispin A
  • Note
    Research use only, not for human use.
  • Brief Description
    Ardisiacrispin A has cytotoxic activity toward HepG2 cancer cell with the GI(50) value of 1.56μM.
  • Description
    Ardisiacrispin A has cytotoxic activity toward HepG2 cancer cell with the GI(50) value of 1.56μM, it could inhibit the proliferation of Bel-7402 cells by inducing apoptosis and disassembling microtubule.Ardisiacrispin(A+B) exhibit prominent abilities to inhibit the proliferation of HL-60 cells by blocking the cell cycle at S phase and inducing apoptosis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Deglucocyclamin | LTS-4 | Saxifragifolin B
  • Pathway
    Microbiology/Virology
  • Target
    HSV
  • Recptor
    HSV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    23643-61-0
  • Formula Weight
    1061.22
  • Molecular Formula
    C52H84O22
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    [H][C@@]1(O[C@@H]2[C@H]([C@@H]([C@H](O[C@]2(O[C@H]3CO[C@@](O[C@@H]4C(C)([C@@]([H])([C@@]5(CC4)C)CC[C@@]6(C)[C@@](C)([C@@]7(CC[C@@]65[H])OC8)C[C@H]([C@]98[C@]7(C[C@@](C=O)(CC9)C)[H])O)C)([C@@H]([C@@H]3O)O[C@@]%10([H])[C@@H]([C@H]([C@@H]([C@H](O%10)CO)O)O)O)[H])[H])CO)O)O)OC[C@H]([C@@H]([C@H]1O)O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Pro-apoptotic and microtubule-disassembly effects of ardisiacrispin (A+B), triterpenoid saponins from Ardisia crenata on human hepatoma Bel-7402 cells. J Asian Nat Prod Res. 2008 Jul-Aug;10(7-8):739-46.
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